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Lance Liotta MD, PhD |
Professor |
Email: lliotta@gmu.edu |
Website: http://www.gmu.edu/departments/lifesciences/proteomics/liotta.htm |
Work Phone: 703-993-9444 |
Fax: 703-993-4288 |
Office: 181C Discovery Hall |
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BioSketch:
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Academic Background:
He earned his medical degree from Case Western Reserve Medical School and is licensed to practice medicine in the state of Maryland. Liotta also holds a doctoral degree in biomedical engineering from Case Western Reserve University. |
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Research Interests:
Liotta and Petricoin began their proteomics collaboration in 1997, which led to the formation of the first Interagency Agreement between NCI and FDA to develop and test technologies for proteomic analysis—the study of protein activity in cells—of cancer and other diseases. Their renowned collaboration has produced more than 100 publications and numerous proteomic processes to develop new methods for diagnosis and treatment of diseases. Combining their clinical and research expertise, they invented a new type of protein microarray technology to simultaneously measure multiple protein pathways from a biopsy specimen. Understanding the activity of protein pathways may ultimately lead to personalized medical treatment and significantly impact public health.
In addition to their invention and development of new types of protein microarray technologies, they recently have made several seminal discoveries for biomarker-based research that may assist in the diagnosis of cancer and other diseases. |
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| Recent Publications |
| Mathematical modeling of the cancer cell's control circuitry: paving the way to patient-tailored combination therapy |
| RP Araujo EF Petricoin III LA Liotta |
| Current Signal Transduction Therapies 2007 (in press) |
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| Modeling of protein signaling networks in clinical proteomics |
| DH Geho EFPetricoin III LA Liotta RP Araujo |
| Cold Spring Harbor Symposia on Quantitative Biology 2006 70 1 |
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| A control theoretic paradigm for cell signaling networks: a simple complexity for a sensitive robustness |
| RP Araujo LA Liotta |
| Curr. Opin. Chem. Biol. 2006 10 1 81-87 |
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| The amplified peptidome: the new treasure chest of candidate biomarkers |
| DH Geho LA Liotta EF Petricoin III W Zhou RP Araujo |
| Curr. Opin. Chem. Biol. 2006 10 1 50 |
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| Network-targeted combination therapy: a new concept in cancer treatment |
| RP Araujo C Doran LA Liotta EF Petricoin III |
| Drug Discovery Today: Therapeutic Strategies 2005 1 4 425 |
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