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Dr. Yuntao Wu |
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Assistant Professor |
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Email: ywu8@gmu.edu |
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Website: |
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Work Phone: (703) 993-4299 |
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Fax: (703) 993-4288 |
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Office: Discovery Hall |
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BioSketch:
Education:
Ph.D., Department of Micirbiology and Immunology, Queen's University, Kingston, Ontario, Canada
Employment:
2003-Present
Assistant Professor, National Center for Biodefense and Infectious Disease, Department of Molecular
and Microbiology, George Mason University, Manassas, Virginia
1999-2003
Research Fellow, Laboratory of Molecular Biology, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland (Project: Pre-integration transcription and its Function in HIV Infection of Primary human CD4 T Cells and Macrophages.
Awards and Grants:
2001: The Norman P. Salzman Memorial Award in Virology (runner-up), NIH.
2003: NIH Fellows Award for Research Excellence, NIH.
2005 t0 2007: Targeting brain macrophages by a novel lentiviral vector
NINDS/NIH 1R21 NS051130-01A1
Patents:
HIV-dependent Expression Vector” (U.S. Application No. 60/507,034, DHHS Reference No. E-276-2003/0-US-01 filed 28 Sep 2003
Publications:
Wu, Y. and E. B. Carstens. 1996. Initiation of baculovirus DNA replication: early promoter regions can function as infection-dependent replicating sequences in a plasmid- based replication assay. J Virol 70(10), 6967-72.
Wu, Y. and E. B. Carstens. 1998. A baculovirus single-stranded DNA binding protein, LEF-3, mediates the nuclear localization of the putative helicase P143. Virology 247(1), 32-40.
Wu, Y., G. Liu and E. B. Carstens. 1999. Replication, integration, and packaging of plasmid DNA following cotransfection with baculovirus viral DNA. J Virol 73(7), 5473-80.
Wu, Y. and J. W. Marsh. 2001. Selective transcription and modulation of resting T cell activity by preintegrated HIV DNA. Science 293(5534), 1503-6.
Wu, Y. and J. W. Marsh. 2003. Preintegration transcription is a normal process of HIV infection of T cells. J. Virology 77(19), 10376-10382.
Wu, Y. and J. Marsh. 2003. Gene transcription in HIV infection. Microbes and Infection 5,1023-27
Wu, Y. 2004. HIV-1 gene expression: Lessons from provirus and non-integrated DNA. Retrovirology 1:13
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Academic Background:
Ph.D., Dept. of Microbiology and Immunology, Queen's University, Kingston, Ontario, Canada.
Research Fellow, National Institute of Mental Health, NIH |
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Research Interests:
HIV infection of resting CD4 T cells; lentiviral vector development for targeting HIV infection |
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